Strong scientific understanding and experience in bioinformatics
Experience in pharmaceutical research and in Immunological disease a plus
Design, implement and/or deploy NGS data analysis workflows for data processing, visualization, integration and mining to support novel therapeutic target identification and disease biomarker discovery
Data Analysis: Implement methods for omics data analysis, and interpretation of genomic data sets (e.g., bulk RNA-seq, scRNA-seq, ATAC-Seq)
Data Visualization: Fluency in contemporary data visualization methods like R Shiny , D3
Data Integration: Analyzing diverse datasets (multi-omics) to find relevant drug discovery targets and downstream effects relevant to immune disease
Data Mining: Internal, collaborative, and public databases to assist in the characterization of immune disease
Select and benchmark methods and tools, define and perform appropriate QC measures
Apply and develop innovative analysis approaches when standard methods are not adequate
Interpret and present analysis results to coworkers and collaborators
Follow relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field
Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may propose new avenues of investigation
Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports
Automate processing and results reporting and delivery
Reports and treats data with a high level of integrity and ethics
Complies with applicable regulations; Maintains proper records in accordance with SOPs and policies
The successful candidate will have experience with more than one of the following; analyzing next-generation sequencing (NGS), functional genomics, statistics for big data analysis, or multi-omics data integration
Good knowledge of existing bioinformatics databases and file formats
In-depth understanding of computational methods for NGS analysis and the usage of public data resources required
Strong hands-on skills in relevant programming languages (e.g., R, Python, Shiny, UNIX/Linux, UNIX bash shell scripting, Nextflow), statistical software, cloud computing, visualization tools, and relevant R/Bioconductor packages
Demonstrated ability to produce well-designed and documented code
Familiarity with computational biology tools and experience working with computational biologists to solve problems
Must enjoy working in a multi-disciplinary and collaborative environment
Ability to troubleshoot both individually and as part of a team
Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner
Master’s degree from an accredited institution with one-plus (1+) years of experience in a related scientific discipline (Computer Science, Genomics, Biostatistics or Bioinformatics preferred) OR Bachelor’s degree from an accredited institution with seven-plus (7+) years of experience in a STEM discipline.
