• Independently initiates and completes routine in vivo studies efficiently, with minimal supervision. Interprets experimental outcomes and recommends appropriate follow-up.
• Demonstrates technical proficiency supporting the development and validation of rodent models for cardiometabolic diseases, with an emphasis on kidney disease, under supervision. Experience with cardiovascular rodent models is a plus.
• Applies basic scientific principles with minimal guidance; performs literature searches and extracts relevant information from published protocols.
• Proposes new ideas and technologies, builds support, and implements improvements based on scientific and technical expertise and an understanding of the drug discovery and development process.
• Independently operates and maintains laboratory equipment and troubleshoots issues effectively.
• Communicates work effectively, both orally and in writing; contributes to protocols, procedures, and technical reports; and provides input for scientific reports.
• Records, analyzes, and reports data with a high level of integrity and ethical conduct.
• Complies with applicable regulations and performs all work safely; maintains accurate records in accordance with Standard Operating Procedures and policies.
• Applies knowledge of CKD theory and core scientific principles to conduct in vivo research; direct experience with rodent models of CKD is highly desirable.
• Demonstrates experience with rodent handling, including oral, IP, SC, and IV dosing; blood sampling; health monitoring; and tissue/sample collection.
• Requires moderate physical activity to perform work in the vivarium and laboratory, including (but not limited to) standing for extended durations (>2 hours), working under a biosafety hood/cabinet for extended durations (>2 hours), bending, lifting (up to 20 lbs), squatting, pushing/pulling, and reaching. Also requires daily handling and restraint of small laboratory animals (rats, mice; >50 at a time), often within a specified timeframe.
• Requires use of personal protective equipment (PPE), including respiratory, eye, hand, and foot protection.
• Proven ability to develop, execute, troubleshoot, optimize, and interpret in vivo pharmacology models; experience dosing test articles and working in renal-related disease areas (e.g., primary glomerulonephritis or cardio-renal metabolism) is a plus.
• Assists with incorporating new technologies to enhance CKD research. Contributes to the design, execution, and interpretation of non-routine experiments with minimal supervision and supports implementation of experimental approaches that advance department goals.
• Demonstrates scientific curiosity and strong problem-solving and troubleshooting skills.
• Communicates work effectively, both orally and in writing; contributes to protocols, procedures, and technical reports; and provides input for scientific reports.
• Ability and willingness to work effectively in a highly collaborative environment and support weekend work as needed.
Master’s Degree with 0 years experience or Bachelor’s Degree with 3+ years experience in related scientific discipline; pharmaceutical, biotechnology or CRO experience is highly desirable; non-PhD applicant required.
