• Plan, coordinate and perform high throughput expression of biotherapeutic proteins using suspension CHO cells at various scales (plate based, tube based and flask based) with automated platforms; Determine key cell-culture parameters and interpret findings.
• Transfection, Culture monitoring, Harvest, Titer determination and Western blot analysis as needed.
• Design and produce DNA for use in transient and stable transfections. Perform molecular biology techniques as necessary: cloning, DNA scale up, sequencing analysis
• Evaluate new technologies and process changes to improve the productivity, quality and consistency of the expression processes.
• Independently interpret, communicate and present results through reports and internal presentations.
• Work closely with counterparts from other functional areas to deliver on research milestones while adhering to broad project timelines.
• Comply with all applicable regulations, perform all work in a safe manner; maintain proper records in accordance with SOP’s and policies.
• Contributes to lab organization, reagent tracking and other tasks as determined appropriate
Thorough understanding of cell culture basics.
• Hands-on experience in cell culture (mammalian) and exceptional aseptic techniques.
• Strong attention to details and excellent organizational skills.
• Able to learn quickly and excel in a past-faced work environment; self-motivation, adaptability and positive attitude.
• Hands-on experience in handling automation/HTP antibody expression is a plus
• Ability to work in plate based formats (24 well, 96 well)
• Knowledge of DNA and molecular biology including basic DNA quality assessments
• Apply knowledge of basic theory and scientific principles
• Concise and accurate reporting of technical data and information
• Ability to troubleshoot and multi-task
• Ability to work in team-oriented environment
• Excellent written and verbal communication skills
• Bachelor’s Degree from an accredited institution with three-plus (3+) years of experience in related scientific discipline, or Master’s Degree from an accredited institution in related scientific discipline or equivalent experience in related field